python - Subnetwork analysis on proteomics data -


background: have proteomics data 7 samples (pvalue/ log-score of fold change), want analyze data network (interactome) analyses.

question: create interactome of proteins data, , map proteins network have significant pvalue (compare control), after create subnetwork(s); add pathways enrichments subnetwork(s).

request: please suggest online or standalone tools (or algorithm) fits requirements.

thanks !

for creating network graphs represent protein-protein interactions, recommend taking @ networkx library. can use pass in nodes (proteins of interest) , edges (interactions) , generate graph. believe can generate subnetworks of these graphs well.


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